American Chemical Society
ol800765s_si_002.cif (9.78 kB)

Carbon Tetrabromide-Mediated Carbon−Sulfur Bond Formation via a Sulfenyl Bromide Intermediate

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Version 2 2016-06-03, 23:27
Version 1 2016-02-27, 11:33
posted on 2008-06-19, 00:00 authored by Jing Tan, Fushun Liang, Yeming Wang, Xin Cheng, Qun Liu, Hongjuan Yuan
In the presence of carbon tetrabromide, a variety of dithiocarbamates, xanthates, dithioesters, and thioethers were prepared in one pot by reacting the corresponding dithioic acids or thiols with active methylene compounds/indole derivatives under mild conditions. The formation of a sulfenyl bromide intermediate is proposed as the key step, which initiates the C−S bond formation.