ol901923x_si_004.cif (18.6 kB)

Brønsted Acid-Promoted Glycosylations of Disaccharide Glycal Substructures of the Saccharomicins

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posted on 05.11.2009, 00:00 by Bradley R. Balthaser, Frank E. McDonald
An acid-promoted glycosylation and alkynol cycloisomerization sequence provided direct access to the 2-deoxytrisaccharide corresponding to the fucose−saccharosamine−digitoxose substructure of saccharomicin B. In the course of this work, the absolute stereochemistry of the repeating fucose−saccharosamine disaccharide of saccharomicins was also confirmed.