Asymmetry by Electrophilic Rearrangement of Symmetric 2-Pyridone Photodimers
datasetposted on 24.11.2005 by Yeon-Hee Lim, Tindy Li, Peiling Chen, Patrick Schreiber, Larissa Kuznetsova, Patrick J. Carroll, Joseph W. Lauher, Scott McN. Sieburth
Datasets usually provide raw data for analysis. This raw data often comes in spreadsheet form, but can be any collection of data, on which analysis can be performed.
Halogenation of achiral trans-2-pyridone photodimers results in 1,3-migration of an amide nitrogen and formation of a chiral structure with six stereogenic centers and well-differentiated functionality. The reactivity of this product toward nucleophiles, including the allylic halide, is dominated by participation by the amide nitrogen.