cm2029855_si_003.cif (12.69 kB)
Download fileAssembly, Two-Photon Absorption, and Bioimaging of Living Cells of A Cuprous Cluster
dataset
posted on 2012-03-13, 00:00 authored by Xuchun Wang, Xiaohe Tian, Qiong Zhang, Pingping Sun, Jieying Wu, Hongping Zhou, Baokang Jin, Jiaxiang Yang, Shengyi Zhang, Chuankui Wang, Xutang Tao, Minhua Jiang, Yupeng TianA novel cuprous(I) cluster Cu4I4L4 (L = (E)-(4-diethylanilino-styryl)pyridine)
bearing
strong two-photon absorption (TPA) was obtained using a facile assembly
method, and the crystal structure has been determined. Quantum chemical
calculations using time-dependent density functional theory (TD-DFT)
reveals that the combination of the organic ligands with the three-dimensional
Cu4I4 core extends the electronic delocalization
in the cluster, leading to strong two-photon absorption action. The
TPA cross sections (Φσ2) of Cu4I4L4 were enhanced with increasing polarity of solvents,
which is quite different from the solvent effects on TPA in the literature.
Compared to its free ligand, the cluster Cu4I4L4 exhibits larger peak TPA cross sections in the near-infrared
region, longer fluorescence lifetimes, higher quantum yield and photostability,
lower cytotoxicity, and brighter two-photon fluorescent (TPF) bioimaging.
These integrated advantages make it desirable to be applied as a two-photon
fluorescent probe for labeling the nucleic acids in live cells.