An Allylpalladium(IV) Intermediate in the Synthesis of Highly Substituted Benzoxepines and Benzopyrans via Reactions of Stable Pallada(II)cycles with Allyl Bromides
datasetposted on 03.04.2020 by Ruiyun Guo, Janelle L. Portscheller, Victor W. Day, Helena C. Malinakova
Datasets usually provide raw data for analysis. This raw data often comes in spreadsheet form, but can be any collection of data, on which analysis can be performed.
Stable pallada(II)cycles L2Pd-1-C6H5-2-OCHCO2Et, featuring a Pd-bonded sp3-hybridized stereogenic carbon and bipyridine or bis(imine) auxiliary ligands (L-L), reacted with allyl bromides via a Pd(II)−Pd(IV)-mediated process involving a direct C(sp2)−H functionalization to afford highly substituted benzoxepines or benzopyrans. An allylpalladium(IV) complex, which was detected by low-temperature 1H NMR analysis and characterized by X-ray crystallography, was shown to operate as an intermediate in the reaction sequence.