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ol403083e_si_003.cif (13.8 kB)

AgF-Mediated Fluorinative Homocoupling of gem-Difluoroalkenes

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posted on 2014-01-03, 00:00 authored by Bing Gao, Yanchuan Zhao, Chuanfa Ni, Jinbo Hu
A novel silver­(I)-fluoride-mediated homocoupling reaction of β,β-difluoro­styrene derivatives is described. The transformation is initiated via nucleophilic addition of silver­(I) fluoride to β,β-difluoro­styrenes, which is followed by dimerization of the corresponding benzyl­silver intermediates. The reaction shows good substrate scope, functional group tolerance, and represents the first report on the reactivity of (α-tri­fluoro­methyl)­benzyl­silver species.

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