ol403083e_si_003.cif (13.8 kB)
AgF-Mediated Fluorinative Homocoupling of gem-Difluoroalkenes
dataset
posted on 2014-01-03, 00:00 authored by Bing Gao, Yanchuan Zhao, Chuanfa Ni, Jinbo HuA novel
silver(I)-fluoride-mediated homocoupling reaction of β,β-difluorostyrene
derivatives is described. The transformation is initiated via nucleophilic
addition of silver(I) fluoride to β,β-difluorostyrenes,
which is followed by dimerization of the corresponding benzylsilver
intermediates. The reaction shows good substrate scope, functional
group tolerance, and represents the first report on the reactivity
of (α-trifluoromethyl)benzylsilver species.