ol5b01607_si_003.cif (896.58 kB)
Download fileAddition of Trifluoroborates to Oxetanyl N,O‑Acetals: Entry into Spiro and Fused Saturated Heterocycles
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posted on 2015-07-02, 00:00 authored by Patrick
B. Brady, Erick M. CarreiraN,O-Acetals derived from 3-oxetanone
and 1,2-amino alcohols undergo addition reactions with alkynyl-, allyl-,
allenyl-, and vinylpotassium trifluoroborates. The resulting products
undergo cyclization by orthogonal activation of the oxetane and the
alkyne to give a diverse set of spiro and fused heterocycles.