American Chemical Society
ja8b12063_si_001.cif (414 kB)

A Mild and Direct Site-Selective sp2 C–H Silylation of (Poly)Azines

Download (414 kB)
posted on 2018-12-18, 00:00 authored by Yiting Gu, Yangyang Shen, Cayetana Zarate, Ruben Martin
A base-mediated protocol that allows for the site-selective sp2 C–H silylation of azines is described. This method is distinguished by its mild conditions, simplicity and excellent site-selective modulation for a diverse set of azines, even in the context of late-stage functionalization, while exhibiting orthogonal reactivity with classical silylation reactions.