posted on 2018-12-18, 00:00authored byYiting Gu, Yangyang Shen, Cayetana Zarate, Ruben Martin
A base-mediated protocol that allows
for the site-selective sp2 C–H
silylation of azines is described.
This method is distinguished by its mild conditions, simplicity and
excellent site-selective modulation for a diverse set of azines, even
in the context of late-stage functionalization, while exhibiting orthogonal
reactivity with classical silylation reactions.