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A Mild and Direct Site-Selective sp2 C–H Silylation of (Poly)Azines

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posted on 2018-12-18, 00:00 authored by Yiting Gu, Yangyang Shen, Cayetana Zarate, Ruben Martin
A base-mediated protocol that allows for the site-selective sp2 C–H silylation of azines is described. This method is distinguished by its mild conditions, simplicity and excellent site-selective modulation for a diverse set of azines, even in the context of late-stage functionalization, while exhibiting orthogonal reactivity with classical silylation reactions.

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