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A Microwave-Assisted Diastereoselective Multicomponent Reaction To Access Dibenzo[c,e]azepinones: Synthesis and Biological Evaluation

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posted on 2011-04-15, 00:00 authored by Vaibhav P. Mehta, Sachin G. Modha, Eelco Ruijter, Kristof Van Hecke, Luc Van Meervelt, Christophe Pannecouque, Jan Balzarini, Romano V. A. Orru, Erik Van der Eycken
An unprecedented microwave-assisted multicomponent strategy has been elaborated for the fast, efficient, and diastereoselective generation of the dibenzo[c,e]azepinone scaffold. The generated compounds were evaluated for their bioactivity.

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