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A Highly Convergent Synthesis of Tricyclic N-Heterocycles Coupling an Ugi Reaction with a Tandem SN2′-Heck Double Cyclization

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posted on 2010-08-06, 00:00 authored by Renata Riva, Luca Banfi, Andrea Basso, Valentina Cerulli, Giuseppe Guanti, Marcella Pani
A small library of natural product-like compounds has been assembled by coupling an Ugi multicomponent reaction with two postcondensation transformations, carried out in one-pot fashion: a SN2′ cyclization followed by an intramolecular Heck reaction.

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