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A Chiral Pool Approach to the Synthesis of Optically Active Tetrahalo Norbornyl Building Blocks

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posted on 17.07.2008, 00:00 by Faiz Ahmed Khan, Ch. Sudheer
Optical antipodes of the mono- and disubstituted polyhalo norbornyl derivatives were prepared in excellent yields. The monosubstituted derivatives 7 were obtained with good enantiopurities. A kaleidoscopic change in the product formation and distribution was observed by changing the chronology of reactions.

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