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mCPBA-Mediated Intramolecular Oxidative Annulation of ortho-Crotyl or Cinnamyl Arylaldehydes: Synthesis of Benzofused Five‑, Six‑, and Seven-Membered Oxacycles

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posted on 2018-10-23, 00:00 authored by Meng-Yang Chang, Yu-Ting Hsiao, Kai-Hsiang Lai
mCPBA-mediated intramolecular oxidative annulation of ortho-crotyl or cinnamyl arylaldehydes provides chroman, coumaran, isochroman, and tetrahydrobenzo­[c]­oxepine under different reaction conditions. This research investigates the reaction conditions for facile and efficient transformation.

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