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α-Amination of Nitrogen Heterocycles:  Ring-Fused Aminals

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posted on 2008-01-16, 00:00 authored by Chen Zhang, Chandra Kanta De, Rudrajit Mal, Daniel Seidel
Aromatic aminoaldehydes react with cyclic amines to produce ring-fused aminals under thermal conditions. This process is applied to two-step syntheses of the quinazolinone alkaloids deoxyvasicinone and rutaecarpine.

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