ol6b01728_si_001.pdf (6.31 MB)
α‑Amidino Rhodium Carbenes: Key Intermediates for the Preparation of (E)‑2-Aminomethylene-3-oxoindoles and Pyranoindoles
journal contribution
posted on 2016-07-08, 15:04 authored by Jing Qian, Guorong Sheng, Kai Huang, Shaojie Liu, Ping Lu, Yanguang WangRhodium-catalyzed
reactions of 3-diazoindolin-2-imines with aromatic
aldehydes and α,β-unsaturated aldehydes respectively furnished
(E)-2-aminomethylene-3-oxoindoles and pyranoindoles
in moderate to excellent yields with nice functional group tolerance.
The reaction proceeds in a cascade involving α-amidino rhodium
carbene as the key intermediate.