Unexpected Reactivity of Acetylenic ω-Ketoesters toward TBAF and <i>t</i>-BuOK; New Cascade Reactions Affording Allene and Oxetane Derivatives<sup>†</sup>

2001-07-20T00:00:00Z (GMT) by Florence Wendling Michel Miesch
The reactivity of acetylenic ω-ketoesters toward tetra-<i>n</i>-butylammonium fluoride and potassium <i>tert</i>-butoxide was studied. These cascade reactions proceeded smoothly and afforded either electrophilic allene derivatives or highly functionalized oxetane derivatives in moderate to high yields.