ol061948m_si_002.pdf (4.55 MB)
Triethylgallium as a Nonnucleophilic Base to Generate Enolates from Ketones
journal contribution
posted on 2006-10-26, 00:00 authored by Yoshio Nishimura, Yutaka Miyake, Ryo Amemiya, Masahiko YamaguchiTriethylgallium deprotonated cyclic and acyclic ketones at 125−175 °C without forming carbonyl addition products, and the resulting gallium
enolates underwent facile C-benzoylation and an aldol reaction. Unsymmetrical ketones were preferentially enolized at the methylene moiety,
which was under kinetic control.