jo8b03192_si_001.pdf (12.4 MB)
Transition-Metal-Free One-Step Synthesis of Ynamides
journal contribution
posted on 2019-03-07, 00:00 authored by Xianzhu Zeng, Yongliang Tu, Zhenming Zhang, Changming You, Jiao Wu, Zhiying Ye, Junfeng ZhaoA robust
transition-metal-free one-step strategy for the synthesis
of ynamides from sulfonamides and (Z)-1,2-dichloroalkenes
or alkynyl chlorides is presented. This method is not only effective
for internal ynamides but also amenable for terminal ynamides. Various
functional groups, even the vinyl moiety, are compatible, and thus,
this strategy offers the opportunity for further functionalization.
