Total Synthesis of Pseudodehydrothyrsiferol
journal contributionposted on 05.02.2009 by Hideaki Hioki, Masatoshi Motosue, Yasuhiko Mizutani, Akira Noda, Tomoaki Shimoda, Miwa Kubo, Kenichi Harada, Yoshiyasu Fukuyama, Mitsuaki Kodama
Any type of content formally published in an academic journal, usually following a peer-review process.
An enantioselective total synthesis of pseudodehydrothyrsiferol has been accomplished. The synthetic sequence highlights formation of the highly strained tetrahydropyran C-ring by a Mitsunobu-type SN2 reaction with an oxygen nucleophile.