ol061444o_si_002.pdf (5.03 MB)
Total Synthesis of Agelagalastatin
journal contribution
posted on 2006-08-31, 00:00 authored by Yong Joo Lee, Bo-Young Lee, Heung Bae Jeon, Kwan Soo KimThe total synthesis of agelagalastatin, an antineoplastic glycosphingolipid, has been achieved. The synthesis involved an α-selective glycosylation
of the ceramide moiety with the trisaccharide fluoride. The trisaccharide component was constructed employing the CB glycoside method
which permitted a completely α-stereoselective galactofuranosylation.