Total Synthesis and Bioactivity of Some Naturally Occurring Pterulones
2002-02-19T00:00:00Z (GMT) by
The naturally occurring pterulones 1, 3, and 13 were synthesized in high overall yield from readily available methyl 3-(2-propenyl)-4-(2-propenyloxy)benzoate (6) by employing ring-closing metathesis (RCM) as a key step. The biological activities of the synthesized pterulones were tested using cells of Rhodotorula glutinis and Saccharomyces cerevisiae.
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