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Thia-Wittig-like Reactions as a New Route for the Stereoselective Synthesis of (Z)-Fluoroalkenoates

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posted on 1999-10-17, 00:00 authored by David Chevrie, Thierry Lequeux, Jean-Claude Pommelet
Stereoselective syntheses of (Z)-fluoroalkenoates 3ag have been developed in three steps from the readily available fluorosulfide 5 and aldehydes. This preparation, involving a Durst reaction, was highly stereoselective and led to fluoroalkenes in 50−60% overall yields, without purification of intermediates.

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