jo5b01827_si_001.pdf (5.04 MB)
The Mosaic of Rottlerin
journal contribution
posted on 2015-11-06, 00:00 authored by Kenneth
K. C. Hong, Graham E. Ball, David StC. Black, Naresh KumarThe first total synthesis of rottlerin
is described. The methodology
allows the development of potential novel protein kinase C δ
(PKCδ) analogues for better treatment of various diseases. Kamalachalcone
A and dimeric rottlerin were synthesized in a very practical and economical
way using FeCl3 as a catalyst.
