American Chemical Society
Browse
ja065572j_si_001.pdf (652.05 kB)

Template-Directed One-Step Synthesis of Cyclic Trimers by ADMET

Download (652.05 kB)
journal contribution
posted on 2006-12-06, 00:00 authored by Hongyi Hou, Ken C.-F. Leung, Daniela Lanari, Alshakim Nelson, J. Fraser Stoddart, Robert H. Grubbs
A trifurcated template, containing three secondary dialkylammonium ion recognition sites for encirclement by a dibenzo [24]crown-8-containing acyclic diene, is used to promote acyclic diene metatheses (ADMET) catalyzed by ruthenium−alkylidene complexes, affording a cyclic trimer in 55% yield. Following this one-step, threefold ADMET reaction, the resulting cyclic trimer was isolated by preparative HPLC and characterized by NMR spectroscopy and mass spectrometry.

History