cg9b01337_si_001.pdf (676.54 kB)
Temperature Cycling Induced Deracemization of NaClO3 under the Influence of Na2S2O6
journal contribution
posted on 2019-12-06, 14:38 authored by Manon Schindler, Clément Brandel, Woo-Sik Kim, Gérard CoquerelSodium chlorate (NaClO3) is an achiral compound
forming
a chiral crystal in the solid state. It is historically the model
compound used by Viedma to report his discovery of the symmetry breaking
phenomenon now called Viedma ripening. In this paper, a temperature
cycling induced deracemization (TCID) processrecently described
as particularly efficient for organic compound deracemizationwas
developed for NaClO3, and the results were compared to
the well-known Viedma ripening process. While the presence of chiral
impurities usually improves the efficacy of chiral compounds TCID,
we observed that the voluntary addition of an inorganic impurity (sodium
dithionate, Na2S2O6) had an opposite
effect on the TCID process of NaClO3. Indeed, the process
was strongly delayed by the presence of Na2S2O6. This phenomenon was explained by a suitable combination
of crystal growth rate and secondary nucleation rate evaluations.