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Synthesis of the Indolizino[7,6-c]quinoline Alkaloid Isaindigotidione

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posted on 2010-10-15, 00:00 authored by Malik Hellal, Gregory D. Cuny
The first synthesis of isaindigotidione has been developed utilizing a reaction sequence including an asymmetric rhodium-catalyzed 1,4-conjugate addition, an intramolecular aldol reaction, and a lactamization.

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    Organic Letters

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    lactamizationAlkaloidisaindigotidioneconjugatereaction sequenceintramolecular aldol reactionIndolizinosynthesisIsaindigotidioneSynthesi

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