Synthesis of the C6−C21 Segment of
Amphidinolide E

Marshall, James A.; Schaaf, Gregory; Nolting, Andrew

doi:10.1021/ol0523493.s002

ol0523493_si_002.pdf (604.26 kB)

Synthesis of the C6−C21 Segment of Amphidinolide E

journal contribution

posted on 2005-11-10, 00:00 authored by James A. Marshall, Gregory Schaaf, Andrew Nolting

A convergent approach to a C6−C21 segment of the polyketide amphidinolide E has been developed through combination of three subunits by allenylindium bromide-aldehyde addition and Suzuki sp²-sp³ coupling.

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Keywords

Suzuki sp 2 Amphidinolide E convergent approach subunit Synthesi combination allenylindium polyketide amphidinolide E sp 3

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