Synthesis of N‑(α-Fluorovinyl)azoles by the Reaction of Difluoroalkenes with Azoles

A mild and versatile method for the construction of C–N bonds by the reaction of (2,2-difluorovinyl)­arenes with various N–H-containing heterocycles in the presence of K3PO4 has been developed. The reaction proceeded efficiently at room temperature (25 °C) affording the (E)-N-α-fluorovinyl derivatives of azoles 3 in good to excellent yields with relatively high stereoselectivity.