ol026412p_si_001.pdf (3.06 MB)
Supramolecular Association of Dopamine with Immobilized Fluorescent Probes
journal contribution
posted on 2002-08-29, 00:00 authored by Françisco M. Raymo, Mabel A. CejasWe have designed a two-step procedure to coat silica particles with fluorescent 2,7-diazapyrenium dications. The electron-deficient character
of the dications encourages the association of dopamine at the particle/water interface. The supramolecular event produces a significant
decrease in the fluorescence intensity. Model binding studies with catechol and propylamine revealed that the interfacial complexation of
dopamine is dominated by the interaction of its electron-rich dioxyarene fragment with the electron-deficient fluorophore in neutral aqueous
environments.