ol202181g_si_001.pdf (4.55 MB)
Structural Reassignment of Cytosporolides A–C via Biomimetic Synthetic Studies and Reinterpretation of NMR Data
journal contribution
posted on 2011-10-07, 00:00 authored by Justin T. J. Spence, Jonathan H. GeorgeA structure revision for the recently isolated fungal meroterpenoids, cytosporolides A–C, is suggested based on biosynthetic speculation and reinterpretation of existing spectroscopic data. The structure revision is supported by a biomimetic synthetic study, featuring a [4 + 2] cycloaddition reaction between a presumed o-quinone methide intermediate and β-caryophyllene.