ol0625785_si_001.pdf (5.4 MB)
Stereoselective Synthesis of Methyl Monate C
journal contribution
posted on 2006-12-21, 00:00 authored by Livia van Innis, Jean Marc Plancher, István E. MarkóThe stereoselective synthesis of methyl monate C 2 is described using as a key step an ene-intramolecular modified Sakurai cyclization
(IMSC) reaction to prepare tetrahydropyran 5. An asymmetric allylic alkylation, followed by a cross-metathesis, enables the insertion of the
right-hand side chain.