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Stereoselective One-Pot, Three-Component Synthesis of 4-Aryltetrahydropyran via Prins−Friedel−Crafts Reaction

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posted on 2009-03-20, 00:00 authored by U. C. Reddy, S. Bondalapati, Anil K. Saikia
A diastereoselective one-pot, three-component Prins−Friedel−Crafts reaction was developed for the synthesis of 4-aryltetrahydropyran derivatives from the reaction of carbonyl compounds with homoallylic alcohol in the presence of arene promoted by boron trifluoride etherate.

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