ic6b02589_si_001.pdf (2.24 MB)
Selective Formation of Chromogen I from N‑Acetyl‑d‑glucosamine upon Lanthanide Coordination
journal contribution
posted on 2016-12-09, 21:29 authored by Xiu-Ying Zheng, Jun-Bo Peng, M. M. Varuni S. Livera, Yun Luo, Ya-Yun Wang, Xiang-Jian Kong, La-Sheng Long, Zhiping Zheng, Lan-Sun ZhengWe report two nonanuclear
lanthanide complexes, [Ln9(μ4-O)(μ3-OH)8(LH)4(OAc)4(H2O)12]·5ClO4·24H2O (Ln
= Gd, 1; Dy, 2), where LH2– is the doubly deprotonated chiral ligand Chromogen I (2-acetamido-2,3-dideoxy-D-erythro-hex-2-enofuranose), one of the many
products from the dehydration of N-acetyl-D-glucosamine (GlcNAc). Mass spectroscopic studies established the
solution stability of these clusters. Through hydrogen bonding, the
cluster complex self-organizes into a nanostructured 54-metal cagelike
assembly featuring six of its units occupying the vertices of an octahedron.
Free Chromogen I can be obtained in pure form and high yield by a
straightforward workup of the cluster complex. This is the first report
of dehydrating GlcNAc without the need of a catalyst or forcing conditions.