np400426a_si_001.pdf (11.6 MB)
Secondary Metabolites from the Chinese Liverwort Cephaloziella kiaeri
journal contribution
posted on 2016-02-18, 19:27 authored by Rui-Juan Li, Rong-Xiu Zhu, Yao-Yao Li, Jin-Chuan Zhou, Jiao-Zhen Zhang, Song Wang, Jian-Ping Ye, Yue-Hu Wang, Susan
L. Morris-Natschke, Kuo-Hsiung Lee, Hong-Xiang LouSixteen new clerodane diterpenoids,
cephaloziellins A–P
(1–16), and two known analogues (17 and 18) were isolated from an EtOH extract
of the Chinese liverwort Cephaloziella kiaeri. The
structures of the new compounds were elucidated from extensive spectroscopic
data (IR, UV, HRESIMS, 1D NMR, and 2D NMR), and the structures of 5, 9, and 15 were confirmed by single-crystal
X-ray diffraction analyses. The absolute configurations of all new
compounds were established by comparing experimental and calculated
electronic circular dichroism spectra.