ol0510522_si_002.cif (29.99 kB)
Salvinicins A and B, New Neoclerodane Diterpenes from Salvia divinorum
dataset
posted on 2005-07-07, 00:00 authored by Wayne W. Harding, Kevin Tidgewell, Matthew Schmidt, Kushal Shah, Christina M. Dersch, John Snyder, Damon Parrish, Jeffrey R. Deschamps, Richard B. Rothman, Thomas E. PrisinzanoTwo new neoclerodane diterpenes, salvinicins A (4) and B (5), were isolated from the dried leaves of Salvia divinorum. The structures of these
compounds were elucidated by spectroscopic techniques, including 1H and 13C NMR, NOESY, HMQC, and HMBC. The absolute stereochemistry
of these compounds was assigned on the basis of single-crystal X-ray crystallographic analysis of salvinicin A (4) and a 3,4-dichlorobenzoate
derivative of salvinorin B.
