jo5002752_si_001.pdf (1.59 MB)
Room-Temperature Ligand-Free Pd/C-Catalyzed C–S Bond Formation: Synthesis of 2‑Substituted Benzothiazoles
journal contribution
posted on 2014-06-20, 00:00 authored by Yannan Cheng, Qian Peng, Weigang Fan, Pixu LiThe
synthesis of 2-substituted benzothiazoles has been achieved
via cyclization of o-iodothiobenzanilide derivatives
using Pd/C as the catalyst at room temperature. The protocol is ligand-free,
additive-free, and high-yielding and involves very mild conditions.