Rhodium(III)-Catalyzed C(sp3)–H Bond Aminocarbonylation with Isocyanates
2018-03-16T00:00:00Z (GMT) by
Rh(III)-catalyzed C(sp3)–H bond aminocarbonylation of 8-methylquinolines and isocyanates has been realized under mild conditions. This approach is applicable to different aryl and alkyl isocyanates, leading to the synthesis of various α-quinolinyl amide compounds in moderate to excellent yields. A plausible mechanism for this transformation is proposed according to the experimental results obtained.