cs9b03380_si_001.pdf (11.84 MB)
Rhodium-Catalyzed Amidation of the Cage B(4)–H Bond in o‑Carboranes with Dioxazolones by Carboxylic Acid-Assisted B(4)–H Bond Activation
journal contribution
posted on 2019-10-18, 13:35 authored by Yonghyeon Baek, Suhui Kim, Jeong-Yu Son, Kooyeon Lee, Dongwook Kim, Phil Ho LeeA rhodium-catalyzed
direct and regioselective amidation of the
cage B(4)–H bond in a wide range of o-carboranes
with alkyl-, aryl-, and heteroaryl-substituted dioxazolones is demonstrated
by carboxylic acid-assisted B(4)–H bond activation in carborane
clusters, providing a number of amidated o-carboranes
in high yields with the release of carbon dioxide. Moreover, the selective
2-fold decarboxylative amidation reaction of the cage B(4)–H
bond in o-carborane was accessed.