Rapid, Mild, and Selective Ketone and Aldehyde Hydroboration/Reduction Mediated by a Simple Lanthanide Catalyst

Rapid, clean hydroboration of ketones and aldehydes with HBpin is achieved using the homoleptic rare-earth catalyst La­[N­(SiMe<sub>3</sub>)<sub>2</sub>]<sub>3</sub> (La<sup>NTMS</sup>). The reaction employs low catalyst loadings (0.01–1 mol % La<sup>NTMS</sup>), proceeds rapidly (>99% in 5 min) at 25 °C, and is moderately air-tolerant. Additionally, this hydroboration has good functional group compatibility, including halides, nitro groups, and nitriles, and is exclusively carbonyl-selective in the presence of alkenes and alkynes.