Probing the Diastereotopicity of Methylene Protons in Strychnine Using Residual Dipolar Couplings
2003-02-04T00:00:00Z (GMT) by
Residual dipolar couplings were successfully used to distinguish between the two diastereotopic protons on C-20 of strychnine dissolved in an organic liquid crystal (PBLG/CDCl3). The results presented here strongly suggest that this method will be of help in organic structure determination, making the determination of relative stereochemistry in the absence of NOE data possible.
CC BY-NC 4.0