jo7b01410_si_002.cif (230.85 kB)
Praseodymium(III)-Catalyzed Regioselective Synthesis of C3‑N-Substituted Coumarins with Coumarins and Azides
dataset
posted on 2017-08-10, 00:00 authored by Jiu-ling Li, Da-chao Hu, Xin-ping Liang, Ying-Chun Wang, Heng-Shan Wang, Ying-ming PanA series of C3-N-substituted
coumarins were synthesized
in good yields directly from coumarins and azides in the presence
of Pr(OTf)3 without any additives or ligands needed. The
selected compounds 3a, 3c–e, 3g, 3i, 3q, 3u, and 3v exhibited good anticancer activities against
MGC-803, A549, and NCI-H460 cell lines with IC50 in the
range 8.75–38.54 μmol L–1.
