Practical Rh(I)-Catalyzed Asymmetric Hydrogenation of β-(Acylamino)acrylates Using a New Unsymmetrical Hybrid Ferrocenylphosphine−Phosphoramidite Ligand:  Crucial Influence of an N−H Proton in the Ligand

Excellent enantioselectivities and high turnovers (S/C = 5000) were achieved in the Rh(I)-catalyzed asymmetric hydrogenation of both β-aryl- and β-alkyl-β-(acylamino)acrylates with a new unsymmetrical hybrid ferrocenylphosphine−phosphoramidite ligand, and the presence of an N−H proton in the ligand was demonstrated to have a crucial role in the enantioselectivity.