Postsynthetic Covalent Modification of a Neutral Metal−Organic Framework

2007-10-17T00:00:00Z (GMT) by Zhenqiang Wang Seth M. Cohen
The covalent modification of the metal−organic framework IRMOF-3 has been achieved using acetic anhydride. Mass spectrometry and <sup>1</sup>H NMR evidence shows that the free amine groups in IRMOF-3 are converted to amides in high yields. Control experiments and X-ray diffraction studies suggest that this reaction occurs on the intact framework with preservation of crystallinity. This finding opens up new possibilities for the preparation of novel MOFs using a postsynthetic modification strategy.