Pitucamycin: Structural Merger of a Phenoxazinone with an Epoxyquinone Antibiotic
2010-09-24T00:00:00Z (GMT) by
Chemical profiling of a Streptomyces griseus strain isolated from an old building with moisture damage led to the discovery of two novel phenoxazinones, chandrananimycin D (1) and pitucamycin (2), along with the known grixazone B (3). Pitucamycin represents an unprecedented hybrid molecule composed of a phenoxazinone and an enaminomycin-like epoxyquinone moiety.
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