Phosphine-Catalyzed Tandem Reaction of Allenoates with Nitroalkenes

2010-11-05T00:00:00Z (GMT) by Xiao-Yang Guan Yin Wei Min Shi
A P(p-FC6H4)3-catalyzed tandem reaction between ethyl 2,3-butadienoate and nitroalkenes has been developed, which involves a [3 + 2] cycloaddition and a subsequent umpolung addition. The asymmetric version of this tandem reaction has also been investigated by using chiral phosphanes.