Phenolic Glycosides with Antioxidant Activity from the Stem Bark of Populus davidiana

Phytochemical study on the EtOAc-soluble fraction of the stem bark of Populus davidiana resulted in the isolation of 10 phenolic glycosides (110), which were identified on the basis of physicochemical and spectroscopic analyses. Among these, three new compounds, populosides A−C (13), were determined to be 2-coumaroylmethyl-4-hydroxyphenyl-β-d-glucopyranoside, 2-coumaroylmethylphenyl-β-d-glucopyranoside, and 2-feruoylmethylphenyl-β-d-glucopyranoside, respectively. Compounds 110 were tested for their radical scavenging activity against an azo radical, ABTS•+. Of these, populosides A−C (13), populoside (4), grandidentatin (8), salireposide (9), and coumaroyl-β-d-glucoside (10) exhibited antioxidant activity in this assay.