ja408864c_si_001.pdf (8.85 MB)
Pd-Catalyzed Enantioselective C–H Iodination: Asymmetric Synthesis of Chiral Diarylmethylamines
journal contribution
posted on 2013-11-06, 00:00 authored by Ling Chu, Xiao-Chen Wang, Curtis
E. Moore, Arnold L. Rheingold, Jin-Quan YuAn
enantioselective C–H iodination reaction using a mono-N-benzoyl-protected amino acid has been developed for the
synthesis of chiral diarylmethylamines. The reaction uses iodine as
the sole oxidant and proceeds at ambient temperature and under air.