ol502749b_si_003.cif (20.88 kB)
Pd-Catalyzed C–H Carbonylation of (Hetero)arenes with Formates and Intramolecular Dehydrogenative Coupling: A Shortcut to Indolo[3,2‑c]coumarins
dataset
posted on 2014-11-21, 00:00 authored by Jie Wu, Jingbo Lan, Siyuan Guo, Jingsong YouAn
efficient protocol for the synthesis of (hetero)aryl carboxylic esters
has been achieved by Pd-catalyzed C–H carbonylation of (hetero)arenes
with aryl formates. A relatively wide range of functional groups can
be tolerated in this transformation, and the corresponding esters
are obtained in good yields. On this basis, an intramolecular oxidative
C–H/C–H coupling has been developed to prepare indolo[3,2-c]coumarins.