Palladium(II) Complexes with Phosphorus−Nitrogen Mixed Donors. Efficient Catalysts for the Heck Reaction

Pd(II) complexes of phosphine−nitrogen (P−N) bidentate donors act as efficient catalysts for the Heck reaction. In a typical example, reaction of phenyl iodide with methyl acrylate in N-methylpyrrolidinone (NMP) at ca. 130 °C provides the Heck product with a turnover number of up to 10⁶. In addition, the coupling reaction of 4-bromoacetophenone with olefin in a quantitative yield was achieved by using the same catalyst in the presence of sodium iodide.