ol401231y_si_001.pdf (1.63 MB)
Palladium-Catalyzed Medium-Ring Formation for Construction of the Core Structure of Laurencia Oxacycles: Synthetic Study of Laurendecumallene B
journal contribution
posted on 2013-06-21, 00:00 authored by Yuji Yoshimitsu, Shinsuke Inuki, Shinya Oishi, Nobutaka Fujii, Hiroaki OhnoPalladium-catalyzed medium-ring formation from a cyclic propargyl carbonate via a ring-opening and -closing cascade proceeded at the central carbon atom of the propargyl unit to provide a tetrahydro-2H-oxocine derivative bearing the core structure of laurencia oxacycle. The synthetic application of this reaction to a possible laurendecumallene B precursor is also presented.