ol201316z_si_003.pdf (526.96 kB)
Organocatalytic Asymmetric Strecker Reaction of Di- and Trifluoromethyl Ketoimines. Remarkable Fluorine Effect
journal contribution
posted on 2011-08-05, 00:00 authored by Yun-Lin Liu, Tao-Da Shi, Feng Zhou, Xiao-Li Zhao, Xin Wang, Jian ZhouA highly enantioselective Strecker reaction of difluoromethyl and trifluoromethyl ketoimines was developed. Remarkable fluorine effect on the reactivity and selectivity is observed and discussed.